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Professor Franck is an expert in the fields of international economic law, dispute settlement, and the empirical analysis of international law. Professor Franck's legal experience includes serving at the United Nations Conference on Trade and Development and practicing in international dispute settlement with Wilmer, Cutler & Pickering [now Wilmer Hale] in Washington, DC and Allen & Overy in London, England. She has been qualified to practice law in England and Wales, Minnesota and the District of Columbia. She is on the Executive Council of the Institute for Transnational Arbitration and the immediate past Chair of the Academic Council, an active member of the American Society of International Law and a former member of the Executive Council, a member of the Chartered Institute of Arbitrators, and an elected member of the American Law Institute.

Professor Franck has made major scholarly and policy contributions into the development of international law and dispute resolution. She is the author of the major 2019 Oxford University Press book, Arbitration Costs: Myths and Realities in Investment Treaty Arbitration, as well as the author of articles in prestigious journals including the American Journal of International Law, Duke Law Journal, Emory Law Journal, Fordham Law Review, Harvard Journal of International Law, Minnesota Law Review, North Carolina Law Review, Virginia Journal of International Law, and Washington University Law Review. In connection with the United Nations Conference on Trade and Development, she organized the Joint Symposium on International Investment and Alternative Dispute Resolution, , and created the summarizing the proceedings, which occurred through a collaboration blog, other online mediums and a traditional in-person conference.

She has presented her research to major international organizations including the Asian Pacific Economic Cooperation (APEC), the International American Development Bank (IADB), the International Centre for Settlement if Investment Disputes (ICSID), and the United Nations Commission on Trade and Investment (UNCTAD), and across the globe in Argentina, Australia, Canada, France, Germany, the Republic of Korea, The Netherlands, Singapore, Sweden, Switzerland, United Kingdom, and United States. Professor Franck has been elected to the International Who's Who of Commercial Arbitration since 2008 and received the "New Voices" award from the American Society of International Law (ASIL) for her groundbreaking empirical analysis of investment treaty arbitration.